ID	5HQ3A	STANDARD;	PRT;	548	AA.
DT	CONVERTED FROM PDB (SEQRES) 5HQ3
DE	Acetylcholinesterase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.600
CC	R-Factor	0.204
FT	#SUB	374	 373 	LEU	A	539	 538 	LYS	B	Protein	S	2
FT	#SUB	374	 373 	LEU	A	540	 539 	LEU	B	Protein	S	2
FT	#SUB	377	 376 	GLU	A	539	 538 	LYS	B	Protein	S	4
FT	#SUB	378	 377 	ALA	A	536	 535 	PHE	B	Protein	A	3
FT	#SUB	381	 380 	LEU	A	382	 381 	HIS	B	Protein	S	1
FT	#SUB	381	 380 	LEU	A	532	 531 	PHE	B	Protein	S	1
FT	#SUB	381	 380 	LEU	A	536	 535 	PHE	B	Protein	S	2
FT	#SUB	382	 381 	HIS	A	381	 380 	LEU	B	Protein	S	1
FT	#SUB	382	 381 	HIS	A	382	 381 	HIS	B	Protein	S	1
FT	#SUB	384	 383 	THR	A	528	 527 	GLN	B	Protein	B	3
FT	#SUB	385	 384 	ASP	A	528	 527 	GLN	B	Protein	A	3
FT	#SUB	386	 385 	TRP	A	527	 526 	ALA	B	Protein	S	1
FT	#SUB	386	 385 	TRP	A	528	 527 	GLN	B	Protein	A	8
FT	#SUB	386	 385 	TRP	A	531	 530 	ALA	B	Protein	S	5
FT	#SUB	386	 385 	TRP	A	535	 534 	ARG	B	Protein	S	7
FT	#SUB	387	 386 	LEU	A	509	 508 	GLN	B	Protein	S	1
FT	#SUB	387	 386 	LEU	A	523	 522 	ARG	B	Protein	S	1
FT	#SUB	387	 386 	LEU	A	524	 523 	GLY	B	Protein	S	1
FT	#SUB	507	 506 	ASP	A	387	 386 	LEU	B	Protein	B	1
FT	#SUB	508	 507 	GLU	A	387	 386 	LEU	B	Protein	B	1
FT	#SUB	528	 527 	GLN	A	384	 383 	THR	B	Protein	S	3
FT	#SUB	528	 527 	GLN	A	385	 384 	ASP	B	Protein	S	3
FT	#SUB	528	 527 	GLN	A	386	 385 	TRP	B	Protein	S	7
FT	#SUB	531	 530 	ALA	A	381	 380 	LEU	B	Protein	A	3
FT	#SUB	531	 530 	ALA	A	386	 385 	TRP	B	Protein	S	5
FT	#SUB	532	 531 	PHE	A	381	 380 	LEU	B	Protein	A	3
FT	#SUB	535	 534 	ARG	A	386	 385 	TRP	B	Protein	S	5
FT	#SUB	536	 535 	PHE	A	378	 377 	ALA	B	Protein	S	4
FT	#SUB	536	 535 	PHE	A	381	 380 	LEU	B	Protein	S	3
FT	#SUB	539	 538 	LYS	A	374	 373 	LEU	B	Protein	B	2
FT	#SUB	539	 538 	LYS	A	377	 376 	GLU	B	Protein	S	5
FT	#SUB	540	 539 	LEU	A	374	 373 	LEU	B	Protein	B	1
FT	#HET	121	 120 	GLY	A	1	601 	VX	A	B	2
FT	#HET	122	 121 	GLY	A	1	601 	VX	A	B	3
FT	#HET	123	 122 	GLY	A	1	601 	VX	A	B	4
FT	#HET	125	 124 	TYR	A	2	602 	MES	A	S	1
FT	#HET	204	 203 	SER	A	1	601 	VX	A	A	13
FT	#HET	205	 204 	ALA	A	1	601 	VX	A	A	5
FT	#HET	237	 236 	TRP	A	1	601 	VX	A	S	3
FT	#HET	287	 286 	TRP	A	2	602 	MES	A	S	13
FT	#HET	294	 293 	SER	A	2	602 	MES	A	B	1
FT	#HET	295	 294 	VAL	A	2	602 	MES	A	A	3
FT	#HET	296	 295 	PHE	A	1	601 	VX	A	S	1
FT	#HET	296	 295 	PHE	A	2	602 	MES	A	B	2
FT	#HET	342	 341 	TYR	A	2	602 	MES	A	S	5
FT	#HET	448	 447 	HIS	A	1	601 	VX	A	S	5
FT	DISORDER	1	5
FT	DISORDER	261	265
FT	DISORDER	495	498
FT	DISORDER	544	548
CC	SEQUENCE	529 AA (ATOM);
CC	DAELLVTTRG GRLRGIRLTT PGGPVSAFLG IPFAEPPVGP RRFRPPEPKQ PWSGVWDATT
CC	FQNVCYQYVD TLYPGFEGTE MWNPNRNLSE DCLYLNVWTP YPRPKNPAPV MVWIYGGGFY
CC	SGSSSLDVYD GRFLVRTERV VLVSMNYRVG AFGFLALPGS REAPGNVGLL DQRLALQWVQ
CC	ENIAAFGGDP TSVTLFGESA GAASVGMHLL SPPSRGLFHR AILQSGAPNA PWAYVSREEA
CC	RRRALQLAKL VGCPPNDTEL VACLRNRPPQ ELVNHEWHVL PQESVFRFSF VPVVDGDFLP
CC	DTPEALINNG DFKGLDVLVG VNKDEGSYFL VYGAPGFSKD NESLISREEF LEGVRVGVPQ
CC	VSDLAAEAIV LHYTDWLHPE DPAKNRDALS DVVGDHNVIC PVAQFAQRYA ANGARVYAYV
CC	FEHRSSTLPW PEWMGVPHGY EIEFIFGIPL DPSRNYTKEE KIFARRLMRY WANFARTGDP
CC	NEPRPQWPPY TADEQKYVSL DLRPLEVRRG LRAQACAFWN RFLPKLLSA
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEGREDAELLVTTRGGRLRGIRLTTPGGPVSAFLGIPFAEPPVGPRRFRP
CC	ATOM   -----DAELLVTTRGGRLRGIRLTTPGGPVSAFLGIPFAEPPVGPRRFRP
CC	            *********************************************
CC	SEQRES PEPKQPWSGVWDATTFQNVCYQYVDTLYPGFEGTEMWNPNRNLSEDCLYL
CC	ATOM   PEPKQPWSGVWDATTFQNVCYQYVDTLYPGFEGTEMWNPNRNLSEDCLYL
CC	       **************************************************
CC	SEQRES NVWTPYPRPKNPAPVMVWIYGGGFYSGSSSLDVYDGRFLVRTERVVLVSM
CC	ATOM   NVWTPYPRPKNPAPVMVWIYGGGFYSGSSSLDVYDGRFLVRTERVVLVSM
CC	       **************************************************
CC	SEQRES NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPTSVTL
CC	ATOM   NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPTSVTL
CC	       **************************************************
CC	SEQRES FGESAGAASVGMHLLSPPSRGLFHRAILQSGAPNAPWAYVSREEARRRAL
CC	ATOM   FGESAGAASVGMHLLSPPSRGLFHRAILQSGAPNAPWAYVSREEARRRAL
CC	       **************************************************
CC	SEQRES QLAKLVGCPPGGTGGNDTELVACLRNRPPQELVNHEWHVLPQESVFRFSF
CC	ATOM   QLAKLVGCPP-----NDTELVACLRNRPPQELVNHEWHVLPQESVFRFSF
CC	       **********     ***********************************
CC	SEQRES VPVVDGDFLPDTPEALINNGDFKGLDVLVGVNKDEGSYFLVYGAPGFSKD
CC	ATOM   VPVVDGDFLPDTPEALINNGDFKGLDVLVGVNKDEGSYFLVYGAPGFSKD
CC	       **************************************************
CC	SEQRES NESLISREEFLEGVRVGVPQVSDLAAEAIVLHYTDWLHPEDPAKNRDALS
CC	ATOM   NESLISREEFLEGVRVGVPQVSDLAAEAIVLHYTDWLHPEDPAKNRDALS
CC	       **************************************************
CC	SEQRES DVVGDHNVICPVAQFAQRYAANGARVYAYVFEHRSSTLPWPEWMGVPHGY
CC	ATOM   DVVGDHNVICPVAQFAQRYAANGARVYAYVFEHRSSTLPWPEWMGVPHGY
CC	       **************************************************
CC	SEQRES EIEFIFGIPLDPSRNYTKEEKIFARRLMRYWANFARTGDPNEPRDPKAPQ
CC	ATOM   EIEFIFGIPLDPSRNYTKEEKIFARRLMRYWANFARTGDPNEPR----PQ
CC	       ********************************************    **
CC	SEQRES WPPYTADEQKYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLD
CC	ATOM   WPPYTADEQKYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA-----
CC	       *******************************************     
SQ	SEQUENCE	548 AA;      MW;         CN;
	MEGREDAELL VTTRGGRLRG IRLTTPGGPV SAFLGIPFAE PPVGPRRFRP PEPKQPWSGV
	WDATTFQNVC YQYVDTLYPG FEGTEMWNPN RNLSEDCLYL NVWTPYPRPK NPAPVMVWIY
	GGGFYSGSSS LDVYDGRFLV RTERVVLVSM NYRVGAFGFL ALPGSREAPG NVGLLDQRLA
	LQWVQENIAA FGGDPTSVTL FGESAGAASV GMHLLSPPSR GLFHRAILQS GAPNAPWAYV
	SREEARRRAL QLAKLVGCPP GGTGGNDTEL VACLRNRPPQ ELVNHEWHVL PQESVFRFSF
	VPVVDGDFLP DTPEALINNG DFKGLDVLVG VNKDEGSYFL VYGAPGFSKD NESLISREEF
	LEGVRVGVPQ VSDLAAEAIV LHYTDWLHPE DPAKNRDALS DVVGDHNVIC PVAQFAQRYA
	ANGARVYAYV FEHRSSTLPW PEWMGVPHGY EIEFIFGIPL DPSRNYTKEE KIFARRLMRY
	WANFARTGDP NEPRDPKAPQ WPPYTADEQK YVSLDLRPLE VRRGLRAQAC AFWNRFLPKL
	LSATDTLD
//
ID	5HQ3B	STANDARD;	PRT;	549	AA.
DT	CONVERTED FROM PDB (SEQRES) 5HQ3
DE	Acetylcholinesterase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.600
CC	R-Factor	0.204
FT	#SUB	374	 373 	LEU	B	539	 538 	LYS	A	Protein	S	2
FT	#SUB	374	 373 	LEU	B	540	 539 	LEU	A	Protein	S	1
FT	#SUB	377	 376 	GLU	B	539	 538 	LYS	A	Protein	S	5
FT	#SUB	378	 377 	ALA	B	536	 535 	PHE	A	Protein	A	4
FT	#SUB	381	 380 	LEU	B	382	 381 	HIS	A	Protein	S	1
FT	#SUB	381	 380 	LEU	B	531	 530 	ALA	A	Protein	S	3
FT	#SUB	381	 380 	LEU	B	532	 531 	PHE	A	Protein	S	3
FT	#SUB	381	 380 	LEU	B	536	 535 	PHE	A	Protein	S	3
FT	#SUB	382	 381 	HIS	B	381	 380 	LEU	A	Protein	S	1
FT	#SUB	382	 381 	HIS	B	382	 381 	HIS	A	Protein	S	1
FT	#SUB	384	 383 	THR	B	528	 527 	GLN	A	Protein	B	3
FT	#SUB	385	 384 	ASP	B	528	 527 	GLN	A	Protein	A	3
FT	#SUB	386	 385 	TRP	B	528	 527 	GLN	A	Protein	A	7
FT	#SUB	386	 385 	TRP	B	531	 530 	ALA	A	Protein	S	5
FT	#SUB	386	 385 	TRP	B	535	 534 	ARG	A	Protein	S	5
FT	#SUB	387	 386 	LEU	B	507	 506 	ASP	A	Protein	B	1
FT	#SUB	387	 386 	LEU	B	508	 507 	GLU	A	Protein	S	1
FT	#SUB	509	 508 	GLN	B	387	 386 	LEU	A	Protein	S	1
FT	#SUB	523	 522 	ARG	B	387	 386 	LEU	A	Protein	B	1
FT	#SUB	524	 523 	GLY	B	387	 386 	LEU	A	Protein	B	1
FT	#SUB	527	 526 	ALA	B	386	 385 	TRP	A	Protein	B	1
FT	#SUB	528	 527 	GLN	B	384	 383 	THR	A	Protein	S	3
FT	#SUB	528	 527 	GLN	B	385	 384 	ASP	A	Protein	S	3
FT	#SUB	528	 527 	GLN	B	386	 385 	TRP	A	Protein	S	8
FT	#SUB	531	 530 	ALA	B	386	 385 	TRP	A	Protein	S	5
FT	#SUB	532	 531 	PHE	B	381	 380 	LEU	A	Protein	B	1
FT	#SUB	535	 534 	ARG	B	386	 385 	TRP	A	Protein	S	7
FT	#SUB	536	 535 	PHE	B	378	 377 	ALA	A	Protein	S	3
FT	#SUB	536	 535 	PHE	B	381	 380 	LEU	A	Protein	S	2
FT	#SUB	539	 538 	LYS	B	374	 373 	LEU	A	Protein	B	2
FT	#SUB	539	 538 	LYS	B	377	 376 	GLU	A	Protein	S	4
FT	#SUB	540	 539 	LEU	B	374	 373 	LEU	A	Protein	B	2
FT	#HET	121	 120 	GLY	B	3	601 	VX	B	B	1
FT	#HET	122	 121 	GLY	B	3	601 	VX	B	B	5
FT	#HET	123	 122 	GLY	B	3	601 	VX	B	B	5
FT	#HET	125	 124 	TYR	B	3	601 	VX	B	S	1
FT	#HET	125	 124 	TYR	B	4	602 	MES	B	S	1
FT	#HET	204	 203 	SER	B	3	601 	VX	B	A	9
FT	#HET	205	 204 	ALA	B	3	601 	VX	B	A	4
FT	#HET	237	 236 	TRP	B	3	601 	VX	B	S	3
FT	#HET	287	 286 	TRP	B	4	602 	MES	B	S	18
FT	#HET	295	 294 	VAL	B	4	602 	MES	B	A	2
FT	#HET	296	 295 	PHE	B	3	601 	VX	B	S	2
FT	#HET	296	 295 	PHE	B	4	602 	MES	B	B	2
FT	#HET	298	 297 	PHE	B	3	601 	VX	B	S	2
FT	#HET	339	 338 	PHE	B	3	601 	VX	B	S	2
FT	#HET	339	 338 	PHE	B	4	602 	MES	B	S	2
FT	#HET	342	 341 	TYR	B	4	602 	MES	B	S	9
FT	#HET	448	 447 	HIS	B	3	601 	VX	B	S	4
FT	DISORDER	1	6
FT	DISORDER	261	265
FT	DISORDER	494	498
FT	DISORDER	545	549
CC	SEQUENCE	528 AA (ATOM);
CC	AELLVTTRGG RLRGIRLTTP GGPVSAFLGI PFAEPPVGPR RFRPPEPKQP WSGVWDATTF
CC	QNVCYQYVDT LYPGFEGTEM WNPNRNLSED CLYLNVWTPY PRPKNPAPVM VWIYGGGFYS
CC	GSSSLDVYDG RFLVRTERVV LVSMNYRVGA FGFLALPGSR EAPGNVGLLD QRLALQWVQE
CC	NIAAFGGDPT SVTLFGESAG AASVGMHLLS PPSRGLFHRA ILQSGAPNAP WAYVSREEAR
CC	RRALQLAKLV GCPPNDTELV ACLRNRPPQE LVNHEWHVLP QESVFRFSFV PVVDGDFLPD
CC	TPEALINNGD FKGLDVLVGV NKDEGSYFLV YGAPGFSKDN ESLISREEFL EGVRVGVPQV
CC	SDLAAEAIVL HYTDWLHPED PAKNRDALSD VVGDHNVICP VAQFAQRYAA NGARVYAYVF
CC	EHRSSTLPWP EWMGVPHGYE IEFIFGIPLD PSRNYTKEEK IFARRLMRYW ANFARTGDPN
CC	EPPQWPPYTA DEQKYVSLDL RPLEVRRGLR AQACAFWNRF LPKLLSAT
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEGREDAELLVTTRGGRLRGIRLTTPGGPVSAFLGIPFAEPPVGPRRFRP
CC	ATOM   ------AELLVTTRGGRLRGIRLTTPGGPVSAFLGIPFAEPPVGPRRFRP
CC	             ********************************************
CC	SEQRES PEPKQPWSGVWDATTFQNVCYQYVDTLYPGFEGTEMWNPNRNLSEDCLYL
CC	ATOM   PEPKQPWSGVWDATTFQNVCYQYVDTLYPGFEGTEMWNPNRNLSEDCLYL
CC	       **************************************************
CC	SEQRES NVWTPYPRPKNPAPVMVWIYGGGFYSGSSSLDVYDGRFLVRTERVVLVSM
CC	ATOM   NVWTPYPRPKNPAPVMVWIYGGGFYSGSSSLDVYDGRFLVRTERVVLVSM
CC	       **************************************************
CC	SEQRES NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPTSVTL
CC	ATOM   NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPTSVTL
CC	       **************************************************
CC	SEQRES FGESAGAASVGMHLLSPPSRGLFHRAILQSGAPNAPWAYVSREEARRRAL
CC	ATOM   FGESAGAASVGMHLLSPPSRGLFHRAILQSGAPNAPWAYVSREEARRRAL
CC	       **************************************************
CC	SEQRES QLAKLVGCPPGGTGGNDTELVACLRNRPPQELVNHEWHVLPQESVFRFSF
CC	ATOM   QLAKLVGCPP-----NDTELVACLRNRPPQELVNHEWHVLPQESVFRFSF
CC	       **********     ***********************************
CC	SEQRES VPVVDGDFLPDTPEALINNGDFKGLDVLVGVNKDEGSYFLVYGAPGFSKD
CC	ATOM   VPVVDGDFLPDTPEALINNGDFKGLDVLVGVNKDEGSYFLVYGAPGFSKD
CC	       **************************************************
CC	SEQRES NESLISREEFLEGVRVGVPQVSDLAAEAIVLHYTDWLHPEDPAKNRDALS
CC	ATOM   NESLISREEFLEGVRVGVPQVSDLAAEAIVLHYTDWLHPEDPAKNRDALS
CC	       **************************************************
CC	SEQRES DVVGDHNVICPVAQFAQRYAANGARVYAYVFEHRSSTLPWPEWMGVPHGY
CC	ATOM   DVVGDHNVICPVAQFAQRYAANGARVYAYVFEHRSSTLPWPEWMGVPHGY
CC	       **************************************************
CC	SEQRES EIEFIFGIPLDPSRNYTKEEKIFARRLMRYWANFARTGDPNEPRDPKAPQ
CC	ATOM   EIEFIFGIPLDPSRNYTKEEKIFARRLMRYWANFARTGDPNEP-----PQ
CC	       *******************************************     **
CC	SEQRES WPPYTADEQKYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDE
CC	ATOM   WPPYTADEQKYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSAT-----
CC	       ********************************************     
SQ	SEQUENCE	549 AA;      MW;         CN;
	MEGREDAELL VTTRGGRLRG IRLTTPGGPV SAFLGIPFAE PPVGPRRFRP PEPKQPWSGV
	WDATTFQNVC YQYVDTLYPG FEGTEMWNPN RNLSEDCLYL NVWTPYPRPK NPAPVMVWIY
	GGGFYSGSSS LDVYDGRFLV RTERVVLVSM NYRVGAFGFL ALPGSREAPG NVGLLDQRLA
	LQWVQENIAA FGGDPTSVTL FGESAGAASV GMHLLSPPSR GLFHRAILQS GAPNAPWAYV
	SREEARRRAL QLAKLVGCPP GGTGGNDTEL VACLRNRPPQ ELVNHEWHVL PQESVFRFSF
	VPVVDGDFLP DTPEALINNG DFKGLDVLVG VNKDEGSYFL VYGAPGFSKD NESLISREEF
	LEGVRVGVPQ VSDLAAEAIV LHYTDWLHPE DPAKNRDALS DVVGDHNVIC PVAQFAQRYA
	ANGARVYAYV FEHRSSTLPW PEWMGVPHGY EIEFIFGIPL DPSRNYTKEE KIFARRLMRY
	WANFARTGDP NEPRDPKAPQ WPPYTADEQK YVSLDLRPLE VRRGLRAQAC AFWNRFLPKL
	LSATDTLDE
//