ID	4DFLA	STANDARD;	PRT;	274	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DFL
DE	Tyrosine-protein kinase SYK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.980
CC	R-Factor	0.199
FT	#HET	15	 377 	LEU	A	1	701 	0K0	A	A	4
FT	#HET	16	 378 	GLY	A	1	701 	0K0	A	B	2
FT	#HET	23	 385 	VAL	A	1	701 	0K0	A	S	4
FT	#HET	38	 400 	ALA	A	1	701 	0K0	A	S	4
FT	#HET	71	 433 	VAL	A	1	701 	0K0	A	S	1
FT	#HET	86	 448 	MET	A	1	701 	0K0	A	S	3
FT	#HET	87	 449 	GLU	A	1	701 	0K0	A	B	3
FT	#HET	88	 450 	MET	A	1	701 	0K0	A	A	4
FT	#HET	89	 451 	ALA	A	1	701 	0K0	A	A	8
FT	#HET	92	 454 	GLY	A	1	701 	0K0	A	B	2
FT	#HET	93	 455 	PRO	A	1	701 	0K0	A	S	1
FT	#HET	95	 457 	ASN	A	3	703 	SO4	A	S	5
FT	#HET	96	 458 	LYS	A	3	703 	SO4	A	S	1
FT	#HET	115	 477 	GLN	A	2	702 	EDO	A	S	2
FT	#HET	136	 498 	ARG	A	1	701 	0K0	A	B	1
FT	#HET	136	 498 	ARG	A	3	703 	SO4	A	S	3
FT	#HET	137	 499 	ASN	A	1	701 	0K0	A	S	2
FT	#HET	139	 501 	LEU	A	1	701 	0K0	A	S	8
FT	#HET	144	 506 	HIS	A	2	702 	EDO	A	B	1
FT	#HET	145	 507 	TYR	A	2	702 	EDO	A	S	2
FT	#HET	149	 511 	SER	A	1	701 	0K0	A	S	2
FT	#HET	150	 512 	ASP	A	1	701 	0K0	A	S	4
FT	DISORDER	18	20
FT	DISORDER	31	32
FT	DISORDER	43	48
CC	SEQUENCE	263 AA (ATOM);
CC	VYLDRKLLTL EDKELGSGTV KKGYYQMVVK TVAVKILPAL KDELLAEANV MQQLDNPYIV
CC	RMIGICEAES WMLVMEMAEL GPLNKYLQQN RHVKDKNIIE LVHQVSMGMK YLEESNFVHR
CC	DLAARNVLLV TQHYAKISDF GLSKALRADE NYYKAQTHGK WPVKWYAPEC INYYKFSSKS
CC	DVWSFGVLMW EAFSYGQKPY RGMKGSEVTA MLEKGERMGC PAGCPREMYD LMNLCWTYDV
CC	ENRPGFAAVE LRLRNYYYDV VNE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPA
CC	ATOM   VYLDRKLLTLEDKELGS---GTVKKGYYQM--VVKTVAVKIL------PA
CC	       *****************   **********  **********      **
CC	SEQRES LKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQ
CC	ATOM   LKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQ
CC	       **************************************************
CC	SEQRES NRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD
CC	ATOM   NRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD
CC	       **************************************************
CC	SEQRES FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLM
CC	ATOM   FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLM
CC	       **************************************************
CC	SEQRES WEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYD
CC	ATOM   WEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYD
CC	       **************************************************
CC	SEQRES VENRPGFAAVELRLRNYYYDVVNE
CC	ATOM   VENRPGFAAVELRLRNYYYDVVNE
CC	       ************************
SQ	SEQUENCE	274 AA;      MW;         CN;
	VYLDRKLLTL EDKELGSGNF GTVKKGYYQM KKVVKTVAVK ILKNEANDPA LKDELLAEAN
	VMQQLDNPYI VRMIGICEAE SWMLVMEMAE LGPLNKYLQQ NRHVKDKNII ELVHQVSMGM
	KYLEESNFVH RDLAARNVLL VTQHYAKISD FGLSKALRAD ENYYKAQTHG KWPVKWYAPE
	CINYYKFSSK SDVWSFGVLM WEAFSYGQKP YRGMKGSEVT AMLEKGERMG CPAGCPREMY
	DLMNLCWTYD VENRPGFAAV ELRLRNYYYD VVNE
//