ID	1DT6A	STANDARD;	PRT;	473	AA.
DT	CONVERTED FROM PDB (SEQRES) 1DT6
DE	CYTOCHROME P450 2C5
OS	Oryctolagus cuniculus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.000
CC	R-Factor	0.241
FT	#HET	94	 112 	ILE	A	5	501 	HEM	A	A	5
FT	#HET	95	 113 	ALA	A	5	501 	HEM	A	A	3
FT	#HET	102	 120 	TRP	A	5	501 	HEM	A	S	1
FT	#HET	106	 124 	ARG	A	5	501 	HEM	A	S	1
FT	#HET	114	 132 	ARG	A	2	503 	SO4	A	S	4
FT	#HET	115	 133 	ASN	A	2	503 	SO4	A	A	3
FT	#HET	120	 138 	LYS	A	3	504 	SO4	A	S	5
FT	#HET	160	 178 	ILE	A	5	501 	HEM	A	S	2
FT	#HET	181	 199 	GLU	A	1	502 	SM	A	S	3
FT	#HET	185	 203 	GLU	A	1	502 	SM	A	S	4
FT	#HET	241	 259 	ASN	A	3	504 	SO4	A	S	1
FT	#HET	243	 261 	ARG	A	3	504 	SO4	A	S	1
FT	#HET	273	 291 	LEU	A	5	501 	HEM	A	A	2
FT	#HET	276	 294 	ALA	A	5	501 	HEM	A	S	4
FT	#HET	277	 295 	GLY	A	5	501 	HEM	A	B	11
FT	#HET	280	 298 	THR	A	5	501 	HEM	A	A	8
FT	#HET	281	 299 	THR	A	5	501 	HEM	A	A	5
FT	#HET	284	 302 	THR	A	5	501 	HEM	A	S	1
FT	#HET	335	 353 	GLN	A	5	501 	HEM	A	S	2
FT	#HET	340	 358 	LEU	A	5	501 	HEM	A	S	1
FT	#HET	341	 359 	LEU	A	5	501 	HEM	A	S	2
FT	#HET	344	 362 	ASN	A	5	501 	HEM	A	S	6
FT	#HET	345	 363 	LEU	A	5	501 	HEM	A	A	4
FT	#HET	347	 365 	HIS	A	5	501 	HEM	A	S	5
FT	#HET	393	 411 	ASP	A	4	505 	SO4	A	A	4
FT	#HET	394	 412 	GLU	A	4	505 	SO4	A	A	4
FT	#HET	400	 418 	LYS	A	4	505 	SO4	A	S	2
FT	#HET	406	 424 	PRO	A	5	501 	HEM	A	B	3
FT	#HET	407	 425 	PHE	A	5	501 	HEM	A	S	7
FT	#HET	408	 426 	SER	A	5	501 	HEM	A	S	6
FT	#HET	412	 430 	ARG	A	5	501 	HEM	A	A	20
FT	#HET	414	 432 	CYS	A	5	501 	HEM	A	A	17
FT	#HET	415	 433 	VAL	A	5	501 	HEM	A	S	4
FT	#HET	416	 434 	GLY	A	5	501 	HEM	A	B	3
FT	#HET	419	 437 	LEU	A	5	501 	HEM	A	S	2
FT	#HET	420	 438 	ALA	A	5	501 	HEM	A	S	2
FT	#HET	423	 441 	GLU	A	5	501 	HEM	A	S	1
FT	DISORDER	1	11
FT	DISORDER	194	204
FT	DISORDER	472	473
CC	SEQUENCE	449 AA (ATOM);
CC	PPGPTPFPII GNILQIDAKD ISKSLTKFSE CYGPVFTVYL GMKPTVVLHG YEAVKEALVD
CC	LGEEFAGRGS VPILEKVSKG LGIAFSNAKT WKEMRRFSLM TLRNFGMGKR SIEDRIQEEA
CC	RCLVEELRKT NASPCDPTFI LGCAPCNVIC SVIFHNRFDY KDEEFLKLME SLHENVELLG
CC	TPLDYFPGIH KTLLKNADYI KNFIMEKVKE HQKLLDVNNP RDFIDCFLIK MEQENNLEFT
CC	LESLVIAVSD LFGAGTETTS TTLRYSLLLL LKHPEVAARV QEEIERVIGR HRSPCMQDRS
CC	RMPYTDAVIH EIQRFIDLLP TNLPHAVTRD VRFRNYFIPK GTDIITSLTS VLHDEKAFPN
CC	PKVFDPGHFL DESGNFKKSD YFMPFSAGKR MCVGEGLARM ELFLFLTSIL QNFKLQSLVE
CC	PKDLDITAVV NGFVSVPPSY QLCFIPIHH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVY
CC	ATOM   -----------PPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVY
CC	                  ***************************************
CC	SEQRES LGMKPTVVLHGYEAVKEALVDLGEEFAGRGSVPILEKVSKGLGIAFSNAK
CC	ATOM   LGMKPTVVLHGYEAVKEALVDLGEEFAGRGSVPILEKVSKGLGIAFSNAK
CC	       **************************************************
CC	SEQRES TWKEMRRFSLMTLRNFGMGKRSIEDRIQEEARCLVEELRKTNASPCDPTF
CC	ATOM   TWKEMRRFSLMTLRNFGMGKRSIEDRIQEEARCLVEELRKTNASPCDPTF
CC	       **************************************************
CC	SEQRES ILGCAPCNVICSVIFHNRFDYKDEEFLKLMESLHENVELLGTPWLQVYNN
CC	ATOM   ILGCAPCNVICSVIFHNRFDYKDEEFLKLMESLHENVELLGTP-------
CC	       *******************************************       
CC	SEQRES FPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQKLLDVNNPRDFIDCFL
CC	ATOM   ----LDYFPGIHKTLLKNADYIKNFIMEKVKEHQKLLDVNNPRDFIDCFL
CC	           **********************************************
CC	SEQRES IKMEQENNLEFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPEVAA
CC	ATOM   IKMEQENNLEFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPEVAA
CC	       **************************************************
CC	SEQRES RVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVT
CC	ATOM   RVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVT
CC	       **************************************************
CC	SEQRES RDVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKK
CC	ATOM   RDVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKK
CC	       **************************************************
CC	SEQRES SDYFMPFSAGKRMCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITA
CC	ATOM   SDYFMPFSAGKRMCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITA
CC	       **************************************************
CC	SEQRES VVNGFVSVPPSYQLCFIPIHHHH
CC	ATOM   VVNGFVSVPPSYQLCFIPIHH--
CC	       *********************  
SQ	SEQUENCE	473 AA;      MW;         CN;
	MAKKTSSKGK LPPGPTPFPI IGNILQIDAK DISKSLTKFS ECYGPVFTVY LGMKPTVVLH
	GYEAVKEALV DLGEEFAGRG SVPILEKVSK GLGIAFSNAK TWKEMRRFSL MTLRNFGMGK
	RSIEDRIQEE ARCLVEELRK TNASPCDPTF ILGCAPCNVI CSVIFHNRFD YKDEEFLKLM
	ESLHENVELL GTPWLQVYNN FPALLDYFPG IHKTLLKNAD YIKNFIMEKV KEHQKLLDVN
	NPRDFIDCFL IKMEQENNLE FTLESLVIAV SDLFGAGTET TSTTLRYSLL LLLKHPEVAA
	RVQEEIERVI GRHRSPCMQD RSRMPYTDAV IHEIQRFIDL LPTNLPHAVT RDVRFRNYFI
	PKGTDIITSL TSVLHDEKAF PNPKVFDPGH FLDESGNFKK SDYFMPFSAG KRMCVGEGLA
	RMELFLFLTS ILQNFKLQSL VEPKDLDITA VVNGFVSVPP SYQLCFIPIH HHH
//