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Ligands
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0E9 Benzyl [(1r,4s,6s,9r)-4,6-dibenzyl-5-hydroxy-1,9-bis(1-methylethyl)-2,8,11-trioxo-13-phenyl-12-oxa-3,7,10-triazatridec-1-yl]carbamate
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Code : 9HVP   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Design, activity and 2.8 Angstroms crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
Release Data : 1992-04-15
Compound :
mol_id molecule chains
1 HIV-1 Protease A,B
Source :
mol_id organism_scientific expression_system
1 Human immunodeficiency virus 1  (taxid:11676) Escherichia coli  (taxid:562)
gene: pol
Authors : Neidhart, D.J., Erickson, J.
Keywords : ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease.

Erickson, J.,Neidhart, D.J.,VanDrie, J.  et al.
(1990)  Science  249 : 527 - 533

PubMed: 2200122

Chain : A, B
UniProt : Q90EB7 (Q90EB7_9HIV1)
Reaction : -