Het-PDB Navi2 (PDB: 6TU9)

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Ligands
Code	Name		Style	Show	Link
0LI	3-(imidazo[1,2-B]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide				PoSSuM

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Download interaction data: 6TU9

Code :

6TU9 PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

The ROR1 Pseudokinase Domain Bound To Ponatinib

Release Data :

2020-01-22

Compound :

mol_id	molecule	chains	synonym
1	Inactive tyrosine-protein kinase transmembrane receptor ROR1	A,B	Neurotrophic tyrosine kinase,receptor-related 1

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Spodoptera frugiperda (taxid:7108)
	gene: ROR1, NTRKR1 expression_system_common: Fall armyworm

Authors :

Mathea, S., Preuss, F., Chatterjee, D., Niininen, W., Ungureanu, D., Shin, D., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S.

Keywords :

Receptor Transmembrane Kinase Pseudokinase Small-molecule inhibitor, SIGNALING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.94 Å )

Citation :

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.

Sheetz, J.B.,Mathea, S.,Karvonen, H. et al.
(2020) Mol.Cell 79 : 390 - 405.e7

PDB ID: 6TU9