PDB ID: 6MNE
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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GOL | Glycerol | PoSSuM | |||
J3Z | (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one | PoSSuM | |||
NAP | Nadp nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
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Download interaction data: 6MNE
Structure summary
Code : | 6MNE PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE AND NADP+ | ||||||||||||
Release Data : | 2019-04-03 | ||||||||||||
Compound : |
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Source : |
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Authors : | Li, T., Lin, S.X. | ||||||||||||
Keywords : | 17BETA-HSD1, ESTRONE, FUNCTIONAL ANALYSES, OXIDOREDUCTASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.8600 Å ) | ||||||||||||
Citation : |
Crystal structures of human 17 beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+reveal the mechanism of substrate inhibition.
Li, T.,Stephen, P.,Zhu, D.W.
et al.
PubMed: 30768851 |
Reaction
Chain : | A, B | ||||||||||||||||
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UniProt : | P14061 (DHB1_HUMAN) | ||||||||||||||||
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