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Ligands
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JSG (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid
Non-standard Residues
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Glycosylation
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Code : 6MHU   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN/Hydrolase
Title : Nucleotide-free Cryo-EM Structure of E.coli LptB2FG Transporter
Release Data : 2019-04-03
Compound :
mol_id molecule chains
1 Lipopolysaccharide export system permease protein LptF F
mol_id molecule chains
2 Lipopolysaccharide export system permease protein LptG G
mol_id molecule chains
3 Lipopolysaccharide export system ATP-binding protein LptB A,B
ec: 3.6.3.-
Source :
mol_id organism_scientific expression_system
1 Escherichia coli (strain K12)  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: lptF, yjgP, b4261, JW4218
mol_id organism_scientific expression_system
2 Escherichia coli (strain K12)  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: lptG, yjgQ, b4262, JW5760
mol_id organism_scientific expression_system
3 Escherichia coli (strain K12)  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: lptB, yhbG, b3201, JW3168
Authors : Orlando, B.J., Li, Y., Liao, M.
Keywords : ABC transporter, lipopolysaccharide, LPS, nanodisc, TRANSPORT PROTEIN-Hydrolase complex
Exp. method : ELECTRON MICROSCOPY ( 4.0 Å )
Citation :

Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.

Li, Y.,Orlando, B.J.,Liao, M.
(2019)  Nature  567 : 486 - 490

PubMed: 30894744
DOI: 10.1038/s41586-019-1025-6

Chain : F
UniProt : P0AF98 (LPTF_ECOLI)
Reaction : -
Chain : G
UniProt : P0ADC6 (LPTG_ECOLI)
Reaction : -
Chain : A, B
UniProt : P0A9V1 (LPTB_ECOLI)
Reaction : -