Het-PDB Navi2 (PDB: 6JXI)

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Ligands
Code	Name	Link
CE1	O-dodecanyl octaethylene glycol	PoSSuM
CLR	Cholesterol	PoSSuM
MF4	Tetrafluoromagnesate(2-)	PoSSuM
MG	Magnesium ion	PoSSuM
PCW	1,2-dioleoyl-sn-glycero-3-phosphocholine	PoSSuM
RB	Rubidium ion	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 6JXI

Code :

6JXI PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN

Title :

Rb+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)

Release Data :

2019-08-14

Compound :

mol_id	molecule	chains	synonym
1	Potassium-transporting ATPase alpha chain 1	A	Gastric H(+)/K(+) ATPase subunit alpha,Proton pump
	ec: 7.2.2.19 mutation: R220C, S593C, Y799W, G1005S

mol_id	molecule	chains	synonym
2	Potassium-transporting ATPase subunit beta	B	Gastric H(+)/K(+) ATPase subunit beta,Proton pump beta chain,gp60-90

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Sus scrofa (taxid:9823)	Pig	Homo sapiens (taxid:9606)
	gene: ATP4A expression_system_variant: GnTI- expression_system_cell_line: HEK293S

mol_id	organism_scientific	organism_common	expression_system
2	Sus scrofa (taxid:9823)	Pig	Homo sapiens (taxid:9606)
	gene: ATP4B expression_system_variant: GnT1- expression_system_cell_line: HEK293S

Authors :

Abe, K., Irie, K.

Keywords :

P-type ATPase, proton pump, gastric, ion pump, MEMBRANE PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.60 Å )

Citation :

A single K + -binding site in the crystal structure of the gastric proton pump.

Yamamoto, K.,Dubey, V.,Irie, K. et al.
(2019) Elife 8

Chain :

UniProt :

P19156 (ATP4A_PIG)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
ATP + H(+)(in) + H2O + K(+)(out) = ADP + 2 H(+)(out) + K(+)(in) + phosphate	7.2.2.19	UniProtKB:P09626, PubMed:19387495, PubMed:29618813, PubMed:30143663, PubMed:31436534
	left-to-right	UniProtKB:P09626

PDB ID: 6JXI