Brand  (β version)

PDB ID: 6HNQ

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Ligands
Code Name Style Show Link
FQ8 [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] [(2~{R},3~{R},4~{S})-2,3,4-tris(oxidanyl)-5-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentoxy]phosphoryl]oxy-pentyl] hydrogen phosphate PoSSuM
MG Magnesium ion PoSSuM
CL Chloride ion PoSSuM
Non-standard Residues
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Structure summary

Code : 6HNQ   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : TarP-6RboP-(CH2)6NH2
Release Data : 2018-10-24
Compound :
mol_id molecule chains synonym
1 Probable ss-1,3-N-acetylglucosaminyltransferase B,C,F,O,P,E,G,Q,A,D,H,I TarP-6RboP-(CH2)6NH2
Source :
mol_id organism_scientific expression_system
1 Staphylococcus aureus subsp. aureus N315  (taxid:158879) Escherichia coli BL21(DE3)  (taxid:469008)
gene: SA1808
Authors : Guo, Y., Stehle, T.
Keywords : Staphylococcus aureus, wall teichoic acid, glycosyltransferase, GT-A fold, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.40 Å )
Citation :

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.

Gerlach, D.,Guo, Y.,De Castro, C.  et al.
(2018)  Nature  563 : 705 - 709

PubMed: 30464342
DOI: 10.1038/s41586-018-0730-x

Reaction

Chain : B, C, F, O, P, E, G, Q, A, D, H, I
UniProt : A0A0H3JNB0 (TARP_STAAN)
Reaction: EC: Evidence:
Physiological Direction:
4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl- beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di- trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D- glucosamine = 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D- ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D- mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis- undecaprenyl diphosphate + n H(+) + n UDP - PubMed:30464342
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