Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
FKZ Octan-1-amine
Modified Residues
Code Name Link
NH2 Amino group
Code : 6H3E
Header : HORMONE
Title : Receptor-bound Ghrelin conformation
Release Data : 2019-07-24
Compound :
mol_id molecule chains synonym
1 Appetite-regulating hormone A Growth hormone secretagogue,Growth hormone-releasing peptide,Motilin-related peptide,Protein M46
mutation: S3D
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
synthetic: yes
Authors : Ferre, G., Damian, M., M'Kadmi, C., Saurel, O., Czaplicki, G., Demange, P., Marie, J., Fehrentz, J.A., Baneres, J.L., Milon, A.
Keywords : Neuropeptide, acyl chain, growth hormone secretagogue receptor, GPCR, lipopeptide hormone, obesity, diabetes, addiction., HORMONE
Exp. method : SOLUTION NMR
Citation :

Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain.

Ferre, G.,Louet, M.,Saurel, O.  et al.
(2019)  Proc.Natl.Acad.Sci.USA  116 : 17525 - 17530

PubMed: 31416915
DOI: 10.1073/pnas.1905105116

Chain : A
UniProt : Q9UBU3 (GHRL_HUMAN)
Reaction : -