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Ligands
Code Name Style Show Link
AYE Prop-2-en-1-amine
GOL Glycerol
SO4 Sulfate ion
Non-standard Residues
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Glycosylation
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Code : 6GZS   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to ubiquitin
Release Data : 2018-11-14
Compound :
mol_id molecule chains synonym
1 Deubiquitinase and deneddylase Dub1 A ChlaDub1
ec: 3.4.22.-
mol_id molecule chains
2 Polyubiquitin-B B
Source :
mol_id organism_scientific expression_system
1 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)  (taxid:471472) Escherichia coli  (taxid:562)
strain: 434/Bu / ATCC VR-902B
gene: cdu1, CTL0247
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: UBB
Authors : Pruneda, J.N., Komander, D.
Keywords : Enzyme, CE clan, Deubiquitinase, Acetyltransferase, hydrolase
Exp. method : X-RAY DIFFRACTION ( 1.900 Å )
Citation :

A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.

Pruneda, J.N.,Bastidas, R.J.,Bertsoulaki, E.  et al.
(2018)  Nat Microbiol  3 : 1377 - 1384

PubMed: 30397340
DOI: 10.1038/s41564-018-0271-y

Chain : A
UniProt : B0B9A0 (CDUB1_CHLT2)
Reaction : -
Chain : B
UniProt : P0CG47 (UBB_HUMAN)
Reaction : -