PDB ID: 6GX3
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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DMF | Dimethylformamide | PoSSuM | |||
FF2 | 4-chloranyl-~{N}-oxidanyl-1-benzothiophene-2-carboxamide | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
K | Potassium ion | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 6GX3
Structure summary
Code : | 6GX3 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal structure of Schistosoma mansoni HDAC8 complexed with an hydroxamate 1 | ||||||||||||
Release Data : | 2018-08-15 | ||||||||||||
Compound : |
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Source : |
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Authors : | Shaik, T.B., Marek, M., Romier, C. | ||||||||||||
Keywords : | Epigenetics, Histone deacetylase, HDAC8, Selective inhibitor, Pathogen, hydrolase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.100 Å ) | ||||||||||||
Citation : |
Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.
Bayer, T.,Chakrabarti, A.,Lancelot, J.
et al.
PubMed: 29806110 |
Reaction
Chain : | A, B, C, D | ||||||||||||||||
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UniProt : | A5H660 (A5H660_SCHMA) | ||||||||||||||||
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