Het-PDB Navi2 (PDB: 6GPL)

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Ligands
Code	Name	Link
BCN	Bicine	PoSSuM
EDO	1,2-ethanediol	PoSSuM
F7E	[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},6~{R})-6-methyl-3,4-bis(oxidanyl)-5-oxidanylidene-oxan-2-yl] hydrogen phosphate	PoSSuM
NAP	Nadp nicotinamide-adenine-dinucleotide phosphate	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 6GPL

Code :

6GPL PDBj RCSB PDB PDBe

Header :

LYASE

Title :

Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man

Release Data :

2018-07-18

Compound :

mol_id	molecule	chains	synonym
1	GDP-mannose 4,6 dehydratase	B,C,D,E	GDP-D-mannose dehydratase,GMD
	ec: 4.2.1.47

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: GMDS

Authors :

Pfeiffer, M., Krojer, T., Johansson, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Nidetzky, B., Oppermann, U., Structural Genomics Consortium (SGC)

Keywords :

Structural Genomics, Structural Genomics Consortium, SGC, Lyase

Exp. method :

X-RAY DIFFRACTION ( 1.76 Å )

Citation :

A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.

Pfeiffer, M.,Johansson, C.,Krojer, T. et al.
(2019) Acs Catalysis 9 : 2962 - 2968

PubMed: 30984471
DOI: 10.1021/acscatal.9b00064

PDB ID: 6GPL

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