Het-PDB Navi2 (PDB: 6GOM)

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Ligands
Code	Name	Link
GNP	Phosphoaminophosphonic acid-guanylate ester	PoSSuM
MG	Magnesium ion	PoSSuM
CIT	Citric acid	PoSSuM
F6E	(6~{S})-1-(1~{H}-imidazol-4-ylcarbonyl)-6-[(4-phenylphenyl)methyl]-4-propyl-1,4-diazepan-5-one	PoSSuM

Non-standard Residues
Code	Name	Show
CSO	S-hydroxycysteine

Glycosylation
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Modification
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Download interaction data: 6GOM

Code :

6GOM PDBj RCSB PDB PDBe

Header :

ONCOPROTEIN

Title :

KRAS-169 Q61H GPPNHP + PPIN-1

Release Data :

2019-02-06

Compound :

mol_id	molecule	chains	synonym
1	GTPase KRas	A,B,C,D,E,F	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
	mutation: Q61H

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: KRAS, KRAS2, RASK2

Authors :

Cruz-Migoni, A., Canning, P., Quevedo, C.E., Carr, S.B., Phillips, S.E.V., Rabbitts, T.H.

Keywords :

KRAS, ONCOPROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.63 Å )

Citation :

Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

Cruz-Migoni, A.,Canning, P.,Quevedo, C.E. et al.
(2019) Proc. Natl. Acad. Sci. U.S.A. 116 : 2545 - 2550

Chain :

A, B, C, D, E, F

UniProt :

P01116 (RASK_HUMAN)

PDB ID: 6GOM