Code : |
6FYY
PDBj
RCSB PDB
PDBe
|
Title : |
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) |
Release Data : |
2018-12-05 |
Compound : |
mol_id |
molecule |
chains |
|
1 |
tRNAi
|
1
|
|
mol_id |
molecule |
chains |
|
2 |
18S ribosomal RNA
|
2
|
|
mol_id |
molecule |
chains |
|
3 |
mRNA (31-MER)
|
3
|
|
mol_id |
molecule |
chains |
|
4 |
40S ribosomal protein S0
|
A
|
|
mol_id |
molecule |
chains |
|
5 |
40S ribosomal protein S1
|
B
|
|
mol_id |
molecule |
chains |
|
6 |
KLLA0F09812p
|
C
|
|
mol_id |
molecule |
chains |
|
7 |
KLLA0D08305p
|
D
|
|
mol_id |
molecule |
chains |
|
8 |
40S ribosomal protein S4
|
E
|
|
mol_id |
molecule |
chains |
|
9 |
KLLA0D10659p
|
F
|
|
mol_id |
molecule |
chains |
|
10 |
40S ribosomal protein S6
|
G
|
|
mol_id |
molecule |
chains |
|
11 |
40S ribosomal protein S7
|
H
|
|
mol_id |
molecule |
chains |
|
12 |
40S ribosomal protein S8
|
I
|
|
mol_id |
molecule |
chains |
|
13 |
KLLA0E23673p
|
J
|
|
mol_id |
molecule |
chains |
|
14 |
KLLA0B08173p
|
K
|
|
mol_id |
molecule |
chains |
|
15 |
KLLA0A10483p
|
L
|
|
mol_id |
molecule |
chains |
|
16 |
40S ribosomal protein S12
|
M
|
|
mol_id |
molecule |
chains |
|
17 |
KLLA0F18040p
|
N
|
|
mol_id |
molecule |
chains |
synonym
|
18 |
40S ribosomal protein S14
|
O
|
RP59
|
mol_id |
molecule |
chains |
|
19 |
KLLA0F07843p
|
P
|
|
mol_id |
molecule |
chains |
|
20 |
40S ribosomal protein S16
|
Q
|
|
mol_id |
molecule |
chains |
|
21 |
KLLA0B01474p
|
R
|
|
mol_id |
molecule |
chains |
|
22 |
KLLA0B01562p
|
S
|
|
mol_id |
molecule |
chains |
|
23 |
KLLA0A07194p
|
T
|
|
mol_id |
molecule |
chains |
|
24 |
KLLA0F25542p
|
U
|
|
mol_id |
molecule |
chains |
|
25 |
40S ribosomal protein S21
|
V
|
|
mol_id |
molecule |
chains |
|
26 |
40S ribosomal protein S22
|
W
|
|
mol_id |
molecule |
chains |
|
27 |
KLLA0B11231p
|
X
|
|
mol_id |
molecule |
chains |
|
28 |
40S ribosomal protein S24
|
Y
|
|
mol_id |
molecule |
chains |
|
29 |
KLLA0B06182p
|
Z
|
|
mol_id |
molecule |
chains |
|
30 |
40S ribosomal protein S26
|
a
|
|
mol_id |
molecule |
chains |
|
31 |
40S ribosomal protein S27
|
b
|
|
mol_id |
molecule |
chains |
synonym
|
32 |
40S ribosomal protein S28
|
c
|
S33
|
mol_id |
molecule |
chains |
|
33 |
40S ribosomal protein S29
|
d
|
|
mol_id |
molecule |
chains |
|
34 |
40S ribosomal protein S30
|
e
|
|
mol_id |
molecule |
chains |
|
35 |
Ubiquitin-40S ribosomal protein S27a
|
f
|
|
mol_id |
molecule |
chains |
|
36 |
KLLA0E12277p
|
g
|
|
mol_id |
molecule |
chains |
synonym
|
37 |
60S ribosomal protein L41-A
|
h
|
L47,Large ribosomal subunit protein eL41-A,YL41
|
mol_id |
molecule |
chains |
synonym
|
38 |
Eukaryotic translation initiation factor 1A
|
i
|
eIF-1A,Eukaryotic translation initiation factor 4C,eIF-4C
|
mol_id |
molecule |
chains |
synonym
|
39 |
Eukaryotic translation initiation factor 2 subunit alpha
|
j
|
eIF-2-alpha
|
mol_id |
molecule |
chains |
synonym
|
40 |
Eukaryotic translation initiation factor 2 subunit gamma
|
k
|
eIF-2-gamma
|
mol_id |
molecule |
chains |
synonym
|
41 |
Eukaryotic translation initiation factor 2 subunit beta
|
l
|
eIF-2-beta
|
mol_id |
molecule |
chains |
synonym
|
42 |
Eukaryotic translation initiation factor 5
|
m
|
eIF-5
|
mol_id |
molecule |
chains |
synonym
|
43 |
Eukaryotic translation initiation factor 3 subunit A
|
o
|
eIF3a,Eukaryotic translation initiation factor 3 110 kDa subunit homolog,eIF3 p110,Translation initiation factor eIF3,p110 subunit homolog
|
mol_id |
molecule |
chains |
synonym
|
44 |
Eukaryotic translation initiation factor 3 subunit B
|
p
|
eIF3b,Cell cycle regulation and translation initiation protein,Eukaryotic translation initiation factor 3 90 kDa subunit,eIF3 p90,Translation initiation factor eIF3 p90 subunit
|
mol_id |
molecule |
chains |
synonym
|
45 |
eIF3c,Eukaryotic translation initiation factor 3 subunit C
|
q
|
eIF3c,Eukaryotic translation initiation factor 3 93 kDa subunit,eIF3 p93,Nuclear transport protein NIP1,Translation initiation factor eIF3,p93 subunit
|
mol_id |
molecule |
chains |
synonym
|
46 |
Eukaryotic translation initiation factor 3 subunit G
|
r
|
eIF3g,Eukaryotic translation initiation factor 3 RNA-binding subunit,eIF-3 RNA-binding subunit,Translation initiation factor eIF3 p33 subunit homolog,eIF3 p33 homolog
|
mol_id |
molecule |
chains |
synonym
|
47 |
Eukaryotic translation initiation factor 3 subunit I
|
s
|
eIF3i,Eukaryotic translation initiation factor 3 39 kDa subunit homolog,eIF-3 39 kDa subunit homolog
|
|
Source : |
mol_id |
organism_scientific |
|
|
1 |
Saccharomyces cerevisiae
(taxid:4932)
|
|
|
mol_id |
organism_scientific |
|
|
2 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
|
|
mol_id |
organism_scientific |
|
|
3 |
Saccharomyces cerevisiae
(taxid:4932)
|
|
|
|
synthetic: yes
|
mol_id |
organism_scientific |
organism_common
|
|
4 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
5 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
6 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
7 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
8 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
9 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
10 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
11 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
12 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
13 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
14 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
15 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
16 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
17 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
18 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
19 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
20 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
21 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
22 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
23 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
24 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
25 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
26 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
27 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
28 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
29 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
30 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
31 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
32 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
33 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
34 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
35 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
36 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
37 |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
(taxid:284590)
|
Yeast
|
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
38 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Escherichia coli BL21(DE3)
(taxid:469008)
|
|
gene: TIF11, YMR260C, YM8156.02C
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
39 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: SUI2, TIF211, YJR007W, J1429
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
40 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: GCD11, TIF213, YER025W
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
41 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: SUI3, TIF212, YPL237W
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
42 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Escherichia coli BL21(DE3)
(taxid:469008)
|
|
gene: TIF5, YPR041W, YP3085.05
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
43 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: RPG1, TIF32, YBR079C, YBR0734
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
44 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: PRT1, CDC63, YOR361C
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
45 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: NIP1, YMR309C, YM9924.01C, YM9952.11C
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
46 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: TIF35, SCY_1313
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
47 |
Saccharomyces cerevisiae
(taxid:4932)
|
Baker's yeast
|
Saccharomyces cerevisiae
(taxid:4932)
|
|
gene: TIF34, SCY_4321
|
|
Authors : |
Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V. |
Keywords : |
ribosome, translation, initiation factors, 40S, eIF1A, eIF3, eIF2, eIF5, tRNAi, 48S PIC, small ribosome subunit |
Exp. method : |
ELECTRON MICROSCOPY ( 3.02 Å ) |
Citation : |
Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Llacer, J.L.,Hussain, T.,Saini, A.K.
et al.
(2018)
Elife
7
PubMed: 30475211
DOI: 10.7554/eLife.39273
|