PDB ID: 6F6S
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Structure summary
Code : | 6F6S PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | VIRAL PROTEIN | ||||||||||||||||||||||||
Title : | CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH benztropine | ||||||||||||||||||||||||
Release Data : | 2018-01-03 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Ren, J., Zhao, Y., Fry, E.E., Stuart, D.I. | ||||||||||||||||||||||||
Keywords : | EBOLA VIRUS, FILOVIRIDAE, ENVELOPE GLYCOPROTEIN, PROTEIN INHIBITOR COMPLEX, IBUPROFEN, benztropine, bepridil, paroxetine, sertraline, TOREMIFENE, VIRAL PROTEIN | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.290 Å ) | ||||||||||||||||||||||||
Citation : |
Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.
Ren, J.,Zhao, Y.,Fry, E.E.
et al.
PubMed: 29272110 Toremifene interacts with and destabilizes the Ebola virus glycoprotein.
Zhao, Y.,Ren, J.,Harlos, K.
et al.
PubMed: 27362232 |
Reaction
Chain : | A |
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UniProt : | Q05320 (VGP_EBOZM) |
Reaction : | - |
Chain : | B |
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UniProt : | A0A0U3BWW0 (A0A0U3BWW0_9MONO) |
Reaction : | - |