PDB ID: 6F3G
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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CJN | ~{N}4,~{N}4-dimethyl-~{N}1-(5-propan-2-ylpyrrolo[3,2-D]pyrimidin-4-yl)cyclohexane-1,4-diamine | PoSSuM |
Code | Name | Show |
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TPO | Phosphothreonine | |
SEP | Phosphoserine |
Code | Name | Emphasize |
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Download interaction data: 6F3G
Structure summary
Code : | 6F3G PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | SIGNALING PROTEIN | ||||||||||||||||||||||||
Title : | IRAK4 IN COMPLEX WITH inhibitor | ||||||||||||||||||||||||
Release Data : | 2018-05-23 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Xue, Y., Degorce, S.L., Robb, G.R., Ferguson, A.D. | ||||||||||||||||||||||||
Keywords : | IRAK4, kinase, inhibitor, cancer, SIGNALING PROTEIN | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.37 Å ) | ||||||||||||||||||||||||
Citation : |
Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4.
Degorce, S.L.,Anjum, R.,Dillman, K.S.
et al.
PubMed: 29398441 |
Reaction
Chain : | B | ||||||||||||
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UniProt : | Q9NWZ3 (IRAK4_HUMAN) | ||||||||||||
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