PDB ID: 6EZ6
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Structure summary
Code : | 6EZ6 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | PI3 kinase delta in complex with Methyl 5-(4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazol-6-yl)-2-methoxynicotinate | ||||||||||||
Release Data : | 2017-12-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Convery, M.A., Campos, S., Dalton, S.E. | ||||||||||||
Keywords : | Covalent inhibitor, kinase, drug discovery, complex, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.04 Å ) | ||||||||||||
Citation : |
Selectively Targeting the Kinome-Conserved Lysine of PI3K delta as a General Approach to Covalent Kinase Inhibition.
Dalton, S.E.,Dittus, L.,Thomas, D.A.
et al.
PubMed: 29232121 |
Reaction
Chain : | A | ||||||||||||||||
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UniProt : | O35904 (PK3CD_MOUSE) | ||||||||||||||||
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