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Ligands
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C05 (2~{R})-2-[(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)sulfanyl]-~{N}-(furan-2-ylmethyl)propanamide
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Code : 6EVQ   PDBj   RCSB PDB   PDBe
Header : PROTEIN BINDING
Title : solution NMR structure of EB1 C terminus (191-260) with a small molecule bound into the SxIP binding site
Release Data : 2018-02-07
Compound :
mol_id molecule chains synonym
1 Microtubule-associated protein RP/EB family member 1 A,B APC-binding protein EB1,End-binding protein 1,EB1
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Escherichia coli  (taxid:562)
gene: Mapre1
Authors : Barsukov, I.L., Almeida, T.B.
Keywords : End-binding protein, EB1, microtubules, SxIP, Microtubule-associated protein RP/EB family member 1, MAPRE1, APC-binding protein EB1, PROTEIN BINDING
Exp. method : SOLUTION NMR
Citation :

Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.

Almeida, T.B.,Carnell, A.J.,Barsukov, I.L.  et al.
(2017)  Sci Rep  7 : 15533 - 15533

PubMed: 29138501
DOI: 10.1038/s41598-017-15502-6

Chain : A, B
UniProt : Q61166 (MARE1_MOUSE)
Reaction : -