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Ligands
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6IR 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-D]imidazol-4-yl]-~{N}-[4-(2-azanylethylsulfamoyl)phenyl]pentanamide
ACT Acetate ion
IR Iridium ion
SO4 Sulfate ion
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Glycosylation
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Code : 6ESU   PDBj   RCSB PDB   PDBe
Header : biotin-binding protein
Title : Artificial imine reductase mutant S112A-N118P-K121A-S122M
Release Data : 2018-01-03
Compound :
mol_id molecule chains
1 Streptavidin A
Source :
mol_id organism_scientific expression_system
1 Streptomyces avidinii  (taxid:1895) Escherichia coli  (taxid:562)
Authors : Hestericova, M., Heinisch, T., Alonso-Cotchico, L., Marechal, J.-D., Vidossich, P., Ward, T.R.
Keywords : streptavidin, beta-barrel, biotin-binding protein
Exp. method : X-RAY DIFFRACTION ( 1.78 Å )
Citation :

Directed Evolution of an Artificial Imine Reductase.

Hestericova, M.,Heinisch, T.,Alonso-Cotchico, L.  et al.
(2018)  Angew. Chem. Int. Ed. Engl.  57 : 1863 - 1868

PubMed: 29265726
DOI: 10.1002/anie.201711016

Chain : A
UniProt : P22629 (SAV_STRAV)
Reaction : -