PDB ID: 6DWE
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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MLI | Malonate ion | PoSSuM | |||
FMT | Formic acid | PoSSuM | |||
P1T | 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acrylic acid | PoSSuM | |||
CS | Cesium ion | PoSSuM | |||
HDJ | (2r,3s,4r)-3-(2',6'-difluoro-4'-methyl[1,1'-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile | PoSSuM | |||
ACT | Acetate ion | PoSSuM | |||
PGE | Triethylene glycol | PoSSuM |
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Download interaction data: 6DWE
Structure summary
Code : | 6DWE PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | LYASE/LYASE INHIBITOR | ||||||||||||||||||||||||
Title : | Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form | ||||||||||||||||||||||||
Release Data : | 2018-07-11 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Chang, C., Michalska, K., Maltseva, N.I., Jedrzejczak, R., McCarren, P., Nag, P.P., Joachimiak, A., Satchell, K., Center for Structural Genomics of Infectious Diseases (CSGID) | ||||||||||||||||||||||||
Keywords : | PLP, heterotetramer, amino acid biosynthesis, substrate channeling, allostery, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, LYASE-LYASE INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.6910 Å ) | ||||||||||||||||||||||||
Citation : |
Crystal structure of tryptophan synthase from M. tuberculosis - closed form with BRD6309 bound
Chang, C.,Michalska, K.,Maltseva, N.I.
et al.
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Reaction
Chain : | A, G, E, C | ||||||||
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UniProt : | P9WFY1 (TRPA_MYCTU) | ||||||||
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Chain : | B, H, F, D | ||||||||
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UniProt : | P9WFX9 (TRPB_MYCTU) | ||||||||
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