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Ligands
Code Name Style Show Link
CA Calcium ion
FZ4 2-aminoethyl diphenylborinate
Non-standard Residues
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Code : 6D7T   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Release Data : 2018-07-18
Compound :
mol_id molecule chains synonym
1 Transient receptor potential cation channel subfamily V member 6 A,B,C,D TrpV6,CaT-like,CaT-L,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2
mutation: Y467A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: TRPV6, ECAC2
Authors : Singh, A.K., Saotome, K., McGoldrick, L.L., Sobolevsky, A.I.
Keywords : Ion channels, transporter, calcium channel, epithelial calcium channel, MEMBRANE PROTEIN
Exp. method : ELECTRON MICROSCOPY ( 4.44 Å )
Citation :

Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.

Singh, A.K.,Saotome, K.,McGoldrick, L.L.  et al.
(2018)  Nat Commun  9 : 2465 - 2465

PubMed: 29941865
DOI: 10.1038/s41467-018-04828-y

Chain : A, B, C, D
UniProt : Q9H1D0 (TRPV6_HUMAN)
Reaction : -