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Ligands
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FY4 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl)amino]methyl}phenyl 4-chlorobenzoate
Non-standard Residues
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Glycosylation
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Code : 6D6L   PDBj   RCSB PDB   PDBe
Header : signaling protein/agonist
Title : The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 14
Release Data : 2018-08-08
Compound :
mol_id molecule chains
1 Transcriptional activator protein LasR A,B,C,D
Source :
mol_id organism_scientific expression_system
1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)  (taxid:208964) Escherichia coli  (taxid:562)
strain: ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1
gene: lasR, PA1430
Authors : Dong, S.H., Nair, S.K.
Keywords : LuxR receptor, SIGNALING PROTEIN, signaling protein-agonist complex
Exp. method : X-RAY DIFFRACTION ( 1.63 Å )
Citation :

Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop "Out" Conformation for LasR.

O'Reilly, M.C.,Dong, S.H.,Rossi, F.M.  et al.
(2018)  Cell Chem Biol  25 : 1128 - 1139.e3

PubMed: 30033130
DOI: 10.1016/j.chembiol.2018.06.007

Chain : A, B, C, D
UniProt : P25084 (LASR_PSEAE)
Reaction : -