Brand  (β version)

PDB ID: 6CZN

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Ligands
Code Name Style Show Link
FNJ 4,4'-[(1r,2r)-1-phenylbutane-1,2-diyl]diphenol PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 6CZN   PDBj   RCSB PDB   PDBe
Header : NUCLEAR PROTEIN
Title : Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Release Data : 2019-03-20
Compound :
mol_id molecule chains synonym
1 Estrogen receptor A,B ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1
mutation: Y537S
mol_id molecule chains
2 GRIP Peptide C,D
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: ESR1, ESR, NR3A1
mol_id organism_scientific expression_system
2 Homo sapiens  (taxid:9606) Synthetic construct  (taxid:32630)
Authors : Fanning, S.W., Han, R., Maximov, P., Jordan, V.C., Greene, G.L.
Keywords : Estrogen Agonist, Breast Cancer, Nuclear Hormone Receptor, NUCLEAR PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.50 Å )
Citation :

Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide

Fanning, S.W.
To Be Published 

Reaction

Chain : A, B
UniProt : P03372 (ESR1_HUMAN)
Reaction : -