Het-PDB Navi2 (PDB: 6CW8)

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Color scheme of protein:

Ligands
Code	Name	Link
ZN	Zinc ion	PoSSuM
K	Potassium ion	PoSSuM
FGY	N-(2,2-dimethylpropyl)-N~2~-[4-(hydroxycarbamoyl)benzene-1-carbonyl]-L-asparaginyl-N-benzyl-L-alaninamide	PoSSuM
EDO	1,2-ethanediol	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 6CW8

Code :

6CW8 PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with RTS-V5

Release Data :

2018-11-21

Compound :

mol_id	molecule	chains
1	Hdac6 protein	A,B
	fragment: residues 288-646

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Danio rerio (taxid:7955)	Zebrafish	Escherichia coli (taxid:562)
	gene: hdac6

Authors :

Osko, J.D., Christianson, D.W.

Keywords :

Histone deacetylase, metallohydrolase, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 1.900 Å )

Citation :

Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor.

Bhatia, S.,Krieger, V.,Groll, M. et al.
(2018) J. Med. Chem. 61 : 10299 - 10309

PDB ID: 6CW8