PDB ID: 6CKC
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Structure summary
Code : | 6CKC PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||||||
Title : | Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity | ||||||||||||||||||||||||
Release Data : | 2018-05-16 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Antonysamy, S. | ||||||||||||||||||||||||
Keywords : | Inhibitor, Complex, TRANSFERASE | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.8000 Å ) | ||||||||||||||||||||||||
Citation : |
LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.
Bonday, Z.Q.,Cortez, G.S.,Grogan, M.J.
et al.
PubMed: 30034588 |
Reaction
Chain : | A | ||||||||
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UniProt : | O14744 (ANM5_HUMAN) | ||||||||
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Chain : | B |
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UniProt : | Q9BQA1 (MEP50_HUMAN) |
Reaction : | - |