PDB ID: 6CJW
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Structure summary
Code : | 6CJW PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE Inhibitor | ||||||||||||
Title : | Crystal Structure of Mnk2-D228G in Complex With Inhibitor | ||||||||||||
Release Data : | 2018-05-09 | ||||||||||||
Compound : |
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Source : |
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Authors : | Han, Q. | ||||||||||||
Keywords : | mnk2 inhibitor, TRANSFERASE-TRANSFERASE Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.38 Å ) | ||||||||||||
Citation : |
Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.
Reich, S.H.,Sprengeler, P.A.,Chiang, G.G.
et al.
PubMed: 29526098 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q9HBH9 (MKNK2_HUMAN) | ||||||||||||
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