PDB ID: 6BY8
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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DMS | Dimethyl sulfoxide | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
FNV | 4-methyl-1-{[(2r)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-D]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1h-indole-2-carbonitrile | PoSSuM | |||
PG4 | Tetraethylene glycol | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 6BY8
Structure summary
Code : | 6BY8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | PROTEIN BINDING | ||||||||||||
Title : | Menin in complex with MI-1482 | ||||||||||||
Release Data : | 2018-11-28 | ||||||||||||
Compound : |
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Source : |
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Authors : | Borkin, T., Klossowski, S., Pollock, J., Linhares, B., Cierpicki, T., Grembecka, J. | ||||||||||||
Keywords : | Protein binding, inhibitor | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.9 Å ) | ||||||||||||
Citation : |
Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction.
Borkin, D.,Klossowski, S.,Pollock, J.
et al.
PubMed: 29738674 |
Reaction
Chain : | A |
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UniProt : | O00255 (MEN1_HUMAN) |
Reaction : | - |