Brand  (β version)

PDB ID: 6B6A

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
9F2 Ceftriaxone PoSSuM
FZS (2r)-2-[(1s)-1-{[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2h-1,3-thiazine-4-carboxylic acid PoSSuM
PO4 Phosphate ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 6B6A   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/ANTIBIOTIC
Title : Beta-Lactamase, 2secs timepoint, mixed, shards crystal form
Release Data : 2018-06-27
Compound :
mol_id molecule chains synonym
1 Beta-lactamase A,B,C,D Ambler class A beta-lactamase
ec: 3.5.2.6
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)  (taxid:83332) Escherichia coli  (taxid:469008)
strain: ATCC 25618 / H37Rv
gene: blaC, blaA, Rv2068c, MTCY49.07c
expression_system_strain: BL21(DE3)
Authors : Pandey, S., Schmidt, M.
Keywords : Beta-Lactamase, ANTIBIOTIC, HYDROLASE-ANTIBIOTIC complex
Exp. method : X-RAY DIFFRACTION ( 2.298 Å )
Citation :

Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.

Olmos, J.L.,Pandey, S.,Martin-Garcia, J.M.  et al.
(2018)  BMC Biol.  16 : 59 - 59

PubMed: 29848358
DOI: 10.1186/s12915-018-0524-5

Reaction

Chain : A, B, C, D
UniProt : P9WKD3 (BLAC_MYCTU)
Reaction: EC: Evidence:
Physiological Direction:
a beta-lactam + H2O = a substituted beta-amino acid 3.5.2.6 PubMed:16870770, PubMed:17915954, PubMed:19251630, PubMed:20353175
-