Het-PDB Navi2 (PDB: 6B5Q)

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Ligands
Code	Name		Style	Show	Link
PGE	Triethylene glycol				PoSSuM

Non-standard Residues
Code	Name	Show
CZS	3-(6-chloro-1,3-benzothiazol-2-yl)-L-alanine
2KY	(2s)-amino(cyclopentyl)ethanoic acid
MLY	N-dimethyl-lysine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
PPI	Propanoic acid
1XY	(4r)-3,4-dihydro-2h-chromen-4-amine

Download interaction data: 6B5Q

Code :

6B5Q PDBj RCSB PDB PDBe

Header :

Ligase/Inhibitor

Title :

DCN1 bound to 38

Release Data :

2018-02-28

Compound :

mol_id	molecule	chains	synonym
1	DCN1-like protein 1	A,B	DCUN1 domain-containing protein 1,Defective in cullin neddylation protein 1-like protein 1,Squamous cell carcinoma-related oncogene

mol_id	molecule	chains
2	Peptidomimetic Inhibitors DI-591	D,E

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: DCUN1D1, DCUN1L1, RP42, SCCRO

mol_id	organism_scientific
2	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Stuckey, J.

Keywords :

E3 ligase, complex, Ligase-Inhibitor complex, LIGASE

Exp. method :

X-RAY DIFFRACTION ( 2.1600 Å )

Citation :

High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction.

Zhou, H.,Zhou, W.,Zhou, B. et al.
(2018) J. Med. Chem. 61 : 1934 - 1950

PDB ID: 6B5Q