Brand  (β version)

PDB ID: 6B1L

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Ligands
Code Name Style Show Link
MYA Tetradecanoyl-CoA PoSSuM
CJ4 1-(5-fluoro-2-{methyl[3-(methylamino)propyl]amino}pyrimidin-4-yl)-N-[(imidazo[1,2-a]pyridin-3-yl)methyl]azetidine-3-carboxamide PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 6B1L   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001173
Release Data : 2018-09-26
Compound :
mol_id molecule chains synonym
1 Glycylpeptide N-tetradecanoyltransferase A,B PlviB.18219.a.FR2
ec: 2.3.1.97
Source :
mol_id organism_scientific expression_system
1 Plasmodium vivax (strain Salvador I)  (taxid:126793) Escherichia coli BL21(DE3)  (taxid:469008)
strain: Salvador I
gene: PVX_085815
expression_system_vector_type: plasmid
Authors : Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Keywords : SSGCID, glycylpeptide N-tetradecanoyltransferase, N-myristoyltransferase, NMT, Plasmodium vivax, Salvador I, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.3000 Å )
Citation :

Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001173

Dranow, D.M.,Horanyi, P.S.,Lorimer, D.D.  et al.
to be published 

Reaction

Chain : A, B
UniProt : A5K1A2 (A5K1A2_PLAVS)
Reaction: EC: Evidence:
Physiological Direction:
N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycyl-[protein] 2.3.1.97 RuleBase:RU000586
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