Het-PDB Navi2 (PDB: 6B11)

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Ligands
Code	Name	Link
HEM	Protoporphyrin ix containing Fe	PoSSuM
CGM	(4r,5s,6s,7r,9r,11e,13e,15s,16r)-16-ethyl-4-hydroxy-5,9,13,15-tetramethyl-2,10-dioxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl 3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranoside	PoSSuM
EDO	1,2-ethanediol	PoSSuM

Non-standard Residues
Code	Name	Show
CSO	S-hydroxycysteine

Glycosylation
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Download interaction data: 6B11

Code :

6B11 PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

TylHI in complex with native substrate 23-deoxy-5-O-mycaminosyl-tylonolide (23-DMTL)

Release Data :

2018-12-19

Compound :

mol_id	molecule	chains	synonym
1	20-oxo-5-O-mycaminosyltylactone 23-monooxygenase	A,B	Cytochrome P-450 monooxygenase TylH1
	ec: 1.14.13.186 other_details: CYS 41 is spontaneously oxidized to sulfenic acid (CSO)

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Streptomyces fradiae (taxid:1906)	Streptomyces roseoflavus	Escherichia coli (taxid:562)
	gene: tylH1, tylHI

Authors :

DeMars, M.D., Sherman, D.H., Podust, L.M.

Keywords :

P450, tylosin biosynthesis, OXIDOREDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 1.9900 Å )

Citation :

TylHI in complex with native substrate 23-deoxy-5-O-mycaminosyl-tylonolide (23-DMTL)

DeMars, M.D.,Sherman, D.H.,Podust, L.M.
To Be Published

PDB ID: 6B11