Het-PDB Navi2 (PDB: 6AZL)

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Ligands
Code	Name		Style	Show	Link
SO4	Sulfate ion				PoSSuM

Non-standard Residues
Code	Name	Show
C67	N~5~-[N-(2-carboxyethyl)carbamimidoyl]-L-ornithine

Glycosylation
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Modification
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Download interaction data: 6AZL

Code :

6AZL PDBj RCSB PDB PDBe

Header :

IMMUNE SYSTEM

Title :

Structure of cetuximab with aminoheptanoic acid-linked N-carboxyethylarginine meditope variant

Release Data :

2017-12-13

Compound :

mol_id	molecule	chains
1	cetuximab Fab light chain	A,C
	other_details: chimeric murine/human antibody; purified from Erbitux

mol_id	molecule	chains
2	cetuximab Fab heavy chain	B,D
	other_details: chimeric murine/human antibody; purified from Erbitux

mol_id	molecule	chains
3	meditope	E,F

Source :

mol_id	organism_scientific	expression_system
1	Homo sapiens (taxid:9606)	Unidentified (taxid:32644)

mol_id	organism_scientific	expression_system
2	Homo sapiens (taxid:9606)	Unidentified (taxid:32644)

mol_id	organism_scientific
3	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Bzymek, K.P., Williams, J.C.

Keywords :

antibody, anti-EGFR, immune system

Exp. method :

X-RAY DIFFRACTION ( 2.482 Å )

Citation :

Meditope-Fab interaction: threading the hole.

Bzymek, K.P.,Ma, Y.,Avery, K.N. et al.
(2017) Acta Crystallogr F Struct Biol Commun 73 : 688 - 694

PDB ID: 6AZL