Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
SO4 Sulfate ion
Modified Residues
Code Name Link
011 7-aminoheptanoic acid
C67 N~5~-[N-(2-carboxyethyl)carbamimidoyl]-L-ornithine
Code : 6AZL
Header : IMMUNE SYSTEM
Title : Structure of cetuximab with aminoheptanoic acid-linked N-carboxyethylarginine meditope variant
Release Data : 2017-12-13
Compound :
mol_id molecule chains
1 cetuximab Fab light chain A,C
other_details: chimeric murine/human antibody; purified from Erbitux
mol_id molecule chains
2 cetuximab Fab heavy chain B,D
other_details: chimeric murine/human antibody; purified from Erbitux
mol_id molecule chains
3 meditope E,F
Source :
mol_id organism_scientific expression_system
1 Homo sapiens  (taxid:9606) Unidentified  (taxid:32644)
mol_id organism_scientific expression_system
2 Homo sapiens  (taxid:9606) Unidentified  (taxid:32644)
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Bzymek, K.P., Williams, J.C.
Keywords : antibody, anti-EGFR, immune system
Exp. method : X-RAY DIFFRACTION ( 2.482 Å )
Citation :

Meditope-Fab interaction: threading the hole.

Bzymek, K.P.,Ma, Y.,Avery, K.N.  et al.
(2017)  Acta Crystallogr F Struct Biol Commun  73 : 688 - 694

PubMed: 29199990
DOI: 10.1107/S2053230X17016272

Chain : A, C
UniProt : P01834 (IGKC_HUMAN)
Reaction : -
Chain : B, D
UniProt : S6B291 (No found in current UniProtKB/SwissProt)
Reaction : -