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Ligands
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9OR 3-[7,8-dimethyl-2,4-bis(oxidanylidene)-10-[(2s,3s,4r)-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentyl]-1h-benzo[G]pteridin-5-yl]-3-oxidanylidene-propanoic acid
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Code : 6A21   PDBj   RCSB PDB   PDBe
Header : FLAVOPROTEIN
Title : Mandelate oxidase mutant-Y128F with the N5-malonyl-FMN adduct
Release Data : 2019-06-19
Compound :
mol_id molecule chains
1 4-hydroxymandelate oxidase A
ec: 1.1.3.46
mutation: Y128F
Source :
mol_id organism_scientific organism_common expression_system
1 Amycolatopsis orientalis  (taxid:31958) Nocardia orientalis Escherichia coli  (taxid:562)
gene: hmo
Authors : Li, T.L., Lin, K.H.
Keywords : FMN-dependent oxidase, FLAVOPROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.501 Å )
Citation :

The flavin mononucleotide cofactor in alpha-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level.

Lyu, S.Y.,Lin, K.H.,Yeh, H.W.  et al.
(2019)  Acta Crystallogr D Struct Biol  75 : 918 - 929

PubMed: 31588923
DOI: 10.1107/S2059798319011938

Chain : A
UniProt : O52792 (HMO_AMYOR)
Reaction: EC: Evidence:
Physiological Direction:
(S)-4-hydroxymandelate + O2 = 4-hydroxyphenylglyoxylate + H2O2 1.1.3.46 PubMed:11137816, PubMed:12240298
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