Brand  (β version)

PDB ID: 6ZU8

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Ligands
Code Name Style Show Link
0WN N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide PoSSuM
ZN Zinc ion PoSSuM
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Structure summary

Code : 6ZU8   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : Crystal structure of human Brachyury G177D variant in complex with Afatinib
Release Data : 2020-08-05
Compound :
mol_id molecule chains synonym
1 Brachyury protein A Protein T
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
Authors : Newman, J.A., Gavard, A.E., Shrestha, L., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
Keywords : Brachyury, TBXT, Afatinib, TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 1.9500 Å )
Citation :

Crystal structure of human Brachyury G177D variant in complex with Afatinib

Newman, J.A.,Gavard, A.E.,Shrestha, L.  et al.
To Be Published 

Reaction

Chain : A
UniProt : O15178 (TBXT_HUMAN)
Reaction : -