PDB ID: 6WXC
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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CMU | 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl) uracil | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
FMT | Formic acid | PoSSuM | |||
PO4 | Phosphate ion | PoSSuM |
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Download interaction data: 6WXC
Structure summary
Code : | 6WXC PDBj RCSB PDB PDBe | ||||||||||||
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Header : | VIRAL PROTEIN | ||||||||||||
Title : | Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with potential repurposing drug Tipiracil | ||||||||||||
Release Data : | 2020-05-20 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kim, Y., Maltseva, N., Jedrzejczak, R., Welk, L., Endres, M., Chang, C., Michalska, K., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | ||||||||||||
Keywords : | SARS Corona virus 2, endoribonuclease, refurbishing drug, COVID-19, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, VIRAL PROTEIN | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.85 Å ) | ||||||||||||
Citation : |
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Kim, Y.,Wower, J.,Maltseva, N.
et al.
PubMed: 33564093 Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2
Kim, Y.,Wower, J.,Maltseva, N.
et al.
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Reaction
Chain : | A, B | ||||||||||||||||||||||||||||||||||||||||
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UniProt : | P0DTD1 (R1AB_SARS2) | ||||||||||||||||||||||||||||||||||||||||
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