Brand  (β version)

PDB ID: 6WFL

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Ligands
Code Name Style Show Link
CAH 5-exo-hydroxycamphor PoSSuM
HEM Protoporphyrin ix containing Fe PoSSuM
K Potassium ion PoSSuM
Non-standard Residues
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Structure summary

Code : 6WFL   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Camphor soaked P450cam D251E
Release Data : 2020-07-08
Compound :
mol_id molecule chains synonym
1 Camphor 5-monooxygenase A Cytochrome P450-cam,Cytochrome P450cam
ec: 1.14.15.1
mutation: D251E
Source :
mol_id organism_scientific expression_system
1 Pseudomonas putida  (taxid:303) Escherichia coli  (taxid:562)
gene: camC, cyp101
Authors : Amaya, J.A., Poulos, T.L., Batabyal, D.
Keywords : P450cam, D251E, camphor, PdX, PdR, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1.

Amaya, J.A.,Batabyal, D.,Poulos, T.L.
(2020)  Biochemistry  59 : 2896 - 2902

PubMed: 32574066
DOI: 10.1021/acs.biochem.0c00329

Reaction

Chain : A
UniProt : P00183 (CPXA_PSEPU)
Reaction: EC: Evidence:
Physiological Direction:
(1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]- [putidaredoxin] = (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin] 1.14.15.1 -
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