Het-PDB Navi2 (PDB: 6VGH)

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Ligands
Code	Name		Style	Show	Link
C3D	(5r,6s)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol				PoSSuM

Non-standard Residues
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Download interaction data: 6VGH

Code :

6VGH PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant In Complex with Lasofoxifene

Release Data :

2020-02-12

Compound :

mol_id	molecule	chains	synonym
1	Estrogen receptor	A,B	ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: ESR1, ESR, NR3A1

Authors :

Fanning, S.W., Greene, G.L.

Keywords :

Breast Cancer, Steroid Receptor, Activating Mutant, Selective Estrogen Receptor Modulator, Antiestrogen, Lasofoxifene, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.1 Å )

Citation :

Ligand Binding Domain

Fanning, S.W.
To Be Published

PDB ID: 6VGH