Het-PDB Navi2 (PDB: 6V4H)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
0EH	(2r)-2-amino-2-methylnonanoic acid
MK8	2-methyl-L-norleucine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
NH2	Amino group

Download interaction data: 6V4H

Code :

6V4H PDBj RCSB PDB PDBe

Header :

APOPTOSIS

Title :

Crystal Structure Analysis of Zebra Fish MDMX

Release Data :

2020-04-22

Compound :

mol_id	molecule	chains	synonym
1	Protein Mdm4	A,C	Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4
	mutation: L46V, V95L

mol_id	molecule	chains
2	Stapled Peptide LSQETF(0EH)DLWKLL(MK8)EN(NH2)	B,D

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Danio rerio (taxid:7955)	Zebrafish	Escherichia coli (taxid:562)
	gene: mdm4, mdmx

mol_id	organism_scientific
2	Homo sapiens (taxid:9606)
	synthetic: yes

Authors :

Seo, H.-S., Dhe-Paganon, S.

Keywords :

apoptosis, p53 binding

Exp. method :

X-RAY DIFFRACTION ( 1.5300 Å )

Citation :

Identification of a Structural Determinant for Selective Targeting of HDMX.

Ben-Nun, Y.,Seo, H.S.,Harvey, E.P. et al.
(2020) Structure 28 : 847 - 857.e5

PDB ID: 6V4H