Brand  (β version)

PDB ID: 6UR4

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
C42 3'-amino-2'-deoxy-cytidine-5'-monophosphate
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 6UR4   PDBj   RCSB PDB   PDBe
Header : REPLICATION/DNA
Title : DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template and 3'-amino primer
Release Data : 2020-03-18
Compound :
mol_id molecule chains
1 DNA polymerase I A
ec: 2.7.7.7
mol_id molecule chains
2 DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*(C42))-3') B
mol_id molecule chains
3 DNA (5'-D(P*CP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3') C
Source :
mol_id organism_scientific expression_system
1 Geobacillus stearothermophilus  (taxid:1422) Escherichia coli  (taxid:562)
gene: DPO1, polA
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Zhang, W., Lelyveld, V.S., Szostak, J.W.
Keywords : amino primer, DNA polymerase, REPLICATION-DNA complex
Exp. method : X-RAY DIFFRACTION ( 2.25 Å )
Citation :

Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase.

Lelyveld, V.S.,Zhang, W.,Szostak, J.W.
(2020)  Proc.Natl.Acad.Sci.USA  117 : 7276 - 7283

PubMed: 32188786
DOI: 10.1073/pnas.1922400117

Reaction

Chain : A
UniProt : D9N168 (D9N168_GEOSE)
Reaction: EC: Evidence:
Physiological Direction:
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) 2.7.7.7 ARBA:ARBA00024632, RuleBase:RU004460
-