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Ligands
Code Name Style Show Link
GOL Glycerol
9YT (2~{S})-4-acetamido-2-azanyl-butanoic acid
Non-standard Residues
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Glycosylation
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Code : 6SJY   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with its product ADABA
Release Data : 2020-01-29
Compound :
mol_id molecule chains synonym
1 L-2,4-diaminobutyric acid acetyltransferase A,C,B DABA acetyltransferase
ec: 2.3.1.178
Source :
mol_id organism_scientific expression_system
1 Geobacillus sp. (strain Y412MC10)  (taxid:481743) Escherichia coli  (taxid:562)
strain: Y412MC10
gene: ectA, GYMC10_5665
Authors : Richter, A.A., Kobus, S., Czech, L., Hoeppner, A., Bremer, E., Smits, S.H.J.
Keywords : L-2, 4-diaminobutyrate acetyltransferase, acetyl coenzyme A, acetylation, stress response, chemical chaperone, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.2000 Å )
Citation :

The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine.

Richter, A.A.,Kobus, S.,Czech, L.  et al.
(2020)  J.Biol.Chem.  295 : 2822 - 2838

PubMed: 31969391
DOI: 10.1074/jbc.RA119.011277

Chain : A, C, B
UniProt : D3EKC1 (D3EKC1_GEOS4)
Reaction: EC: Evidence:
Physiological Direction:
acetyl-CoA + L-2,4-diaminobutanoate = (2S)-4-acetamido-2- aminobutanoate + CoA + H(+) 2.3.1.178 ARBA:ARBA00000400, RuleBase:RU365045
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