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Ligands
Code Name Style Show Link
CL Chloride ion
EDO 1,2-ethanediol
JL2 3-[3-[2-[(3,4,5-trimethoxyphenyl)amino]pyrrolo[2,3-D]pyrimidin-7-yl]phenyl]propanenitrile
Non-standard Residues
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Code : 6QY9   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Human CSNK2A2 bound to a Pyrrolo[2,3-D]pyrimidinyl inhibitor
Release Data : 2019-04-17
Compound :
mol_id molecule chains synonym
1 Casein kinase II subunit alpha' A CK II alpha'
ec: 2.7.11.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
gene: CSNK2A2, CK2A2
expression_system_strain: BL21(DE3)
Authors : Abdul Azeez, K.R., Sorrell, F.J., Krojer, T., Bountra, C., Edwards, A.M., Arrowsmith, C., Knapp, S., Elkins, J.M.
Keywords : Kinase, Structural Genomics Consortium, SGC, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.50 Å )
Citation :

Human CSNK2A2 bound to a Pyrrolo[2,3-d]pyrimidinyl inhibitor

Abdul Azeez, K.R.,Elkins, J.M.
To Be Published 

Chain : A
UniProt : P19784 (CSK22_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 PubMed:11239457, PubMed:20545769, PubMed:21482717, PubMed:30898438
left-to-right PubMed:11239457, PubMed:20545769, PubMed:21482717, PubMed:30898438, PubMed:35597237
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 PubMed:22325354
left-to-right