Brand  (β version)

PDB ID: 6QS5

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Ligands
Code Name Style Show Link
JGB (~{E})-3-[3,4-bis(oxidanyl)phenyl]-2-cyano-prop-2-enamide PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 6QS5   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of maize CK2 in complex with tyrphostin AG99
Release Data : 2019-02-27
Compound :
mol_id molecule chains synonym
1 Casein kinase II subunit alpha A CK II,CK2-alpha
ec: 2.7.11.1
Source :
mol_id organism_scientific expression_system
1 Zea mays  (taxid:4577) Escherichia coli  (taxid:562)
gene: ACK2
Authors : Lolli, G., Mazzorana, M., Battistutta, R.
Keywords : protein kinase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.9610 Å )
Citation :

Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight.

Lolli, G.,Cozza, G.,Mazzorana, M.  et al.
(2012)  Biochemistry  51 : 6097 - 6107

PubMed: 22794353
DOI: 10.1021/bi300531c

Reaction

Chain : A
UniProt : P28523 (CSK2A_MAIZE)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 -
-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 -
-