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Ligands
Code Name Style Show Link
ATP Adenosine-5'-triphosphate
MG Magnesium ion
CV9 (2~{R},3~{R},5~{S},6~{E},8~{E},10~{z},12~{S},13~{R},16~{z},18~{E},20~{z},22~{E},24~{R},25~{S},26~{E},28~{z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one
Non-standard Residues
Code Name Show
HIC 4-methyl-histidine
Glycosylation
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Modification
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Code : 6QRI   PDBj   RCSB PDB   PDBe
Header : CYTOSOLIC PROTEIN
Title : Structure of rabbit G-actin in complex with chivosazole A
Release Data : 2019-07-03
Compound :
mol_id molecule chains synonym
1 Actin, alpha skeletal muscle B,A Alpha-actin-1
Source :
mol_id organism_scientific organism_common expression_system
1 Oryctolagus cuniculus  (taxid:9986) Rabbit Oryctolagus cuniculus  (taxid:9986)
gene: ACTA1, ACTA
expression_system_common: Rabbit
Authors : Schneider, S., Wang, S., Zahler, S.
Keywords : cytoskeleton, macrolide, myxobacteria, CYTOSOLIC PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.4000 Å )
Citation :

Chivosazole A Modulates Protein-Protein Interactions of Actin.

Wang, S.,Gegenfurtner, F.A.,Crevenna, A.H.  et al.
(2019)  J.Nat.Prod.  82 : 1961 - 1970

PubMed: 31260301
DOI: 10.1021/acs.jnatprod.9b00335

Chain : B, A
UniProt : P68135 (ACTS_RABIT)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O = ADP + H(+) + phosphate - UniProtKB:P68137
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