Brand  (β version)

PDB ID: 6QMI

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
9FH 5-methyl-1-phenyl-pyrazole-4-carboxylic acid PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 6QMI   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 3-(1H-indol-1-yl)propanoic acid at 1.7A resolution.
Release Data : 2020-02-26
Compound :
mol_id molecule chains synonym
1 Phosphopantetheine adenylyltransferase A Dephospho-CoA pyrophosphorylase,Pantetheine-phosphate adenylyltransferase,PPAT
ec: 2.7.7.3
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)  (taxid:83332) Escherichia coli BL21(DE3)  (taxid:469008)
strain: ATCC 25618 / H37Rv
gene: coaD, kdtB, Rv2965c, MTCY349.22, u0002e
Authors : Blaszczyk, M., Blundell, T.L.
Keywords : CoaD, PPAT, Transferase, Complex
Exp. method : X-RAY DIFFRACTION ( 1.7810 Å )
Citation :

Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors

Blaszczyk, M.,El Bakali, J.,Boland, J.A.  et al.
To Be Published 

Reaction

Chain : A
UniProt : P9WPA5 (COAD_MYCTU)
Reaction: EC: Evidence:
Physiological Direction:
(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate 2.7.7.3 HAMAP- Rule:MF_00151, PubMed:20851704, Ref.5
-