PDB ID: 6QMC
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Structure summary
Code : | 6QMC PDBj RCSB PDB PDBe | ||||||||||||
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Header : | PROTEIN BINDING | ||||||||||||
Title : | Small molecule inhibitor of the KEAP1-NRF2 protein-protein interaction | ||||||||||||
Release Data : | 2019-04-24 | ||||||||||||
Compound : |
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Source : |
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Authors : | Davies, T.G. | ||||||||||||
Keywords : | Protein ubiquitination, oxidative stress, kelch motif, PROTEIN BINDING | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.77 Å ) | ||||||||||||
Citation : |
Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction.
Heightman, T.D.,Callahan, J.F.,Chiarparin, E.
et al.
PubMed: 30973731 |
Reaction
Chain : | A |
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UniProt : | Q9Z2X8 (KEAP1_MOUSE) |
Reaction : | - |