PDB ID: 6QFQ
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Structure summary
Code : | 6QFQ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | APOPTOSIS | ||||||||||||
Title : | Structure of human Mcl-1 in complex with indole acid inhibitor | ||||||||||||
Release Data : | 2019-06-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Dokurno, P., Murray, J., Davidson, J., Chen, I., Davis, B., Graham, C.J., Harris, R., Jordan, A.M., Matassova, N., Pedder, C., Ray, S., Roughley, S., Smith, J., Walmsley, C., Wang, Y., Whitehead, N., Williamson, D.S., Casara, P., Le Diguarher, T., Hickman, J., Stark, J., Kotschy, A., Geneste, O., Hubbard, R.E. | ||||||||||||
Keywords : | APOPTOSIS, MCL1, BCL2, small molecule inhibitor | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.6000 Å ) | ||||||||||||
Citation : |
Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Murray, J.B.,Davidson, J.,Chen, I.
et al.
PubMed: 31459977 |
Reaction
Chain : | A |
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UniProt : | Q07820 (MCL1_HUMAN) |
Reaction : | - |