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Ligands
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08T [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium
ADP Adenosine-5'-diphosphate
MG Magnesium ion
Non-standard Residues
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Glycosylation
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Code : 6QEM   PDBj   RCSB PDB   PDBe
Header : REPLICATION
Title : E. coli DnaBC complex bound to ssDNA
Release Data : 2019-03-06
Compound :
mol_id molecule chains
1 Replicative DNA helicase A,B,C,D,E,F
ec: 3.6.4.12
mol_id molecule chains
2 DNA replication protein DnaC G,H,I,J,K,L
ec: 3.6.4.12
mol_id molecule chains
3 ssDNA M
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: dnaB, groP, grpA, b4052, JW4012
mol_id organism_scientific expression_system
2 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: dnaC, dnaD, b4361, JW4325
mol_id organism_scientific
3 Escherichia coli  (taxid:562)
synthetic: yes
Authors : Arias-Palomo, E., Puri, N., O'Shea Murray, V.L., Yan, Q., Berger, J.M.
Keywords : Helicase, helicase loader, AAA+, RecA, REPLICATION
Exp. method : ELECTRON MICROSCOPY ( 3.4 Å )
Citation :

Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.

Arias-Palomo, E.,Puri, N.,O'Shea Murray, V.L.  et al.
(2019)  Mol.Cell  74 : 173 - 184.e4

PubMed: 30797687
DOI: 10.1016/j.molcel.2019.01.023

Chain : A, B, C, D, E, F
UniProt : P0ACB0 (DNAB_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O = ADP + H(+) + phosphate 3.6.4.12 -
-
Chain : G, H, I, J, K, L
UniProt : P0AEF0 (DNAC_ECOLI)
Reaction : -