Het-PDB Navi2 (PDB: 6PUU)

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Ligands
Code	Name		Style	Show	Link
CA	Calcium ion				PoSSuM
CV1	(2r,3r,4s,5r,13r,14s,15r,16r)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8 ,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide				PoSSuM

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Download interaction data: 6PUU

Code :

6PUU PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Human TRPM2 bound to 8-Br-cADPR and calcium

Release Data :

2019-09-25

Compound :

mol_id	molecule	chains	synonym
1	Transient receptor potential cation channel subfamily M member 2	A,B,C,D	TRPM2, Estrogen-responsive element-associated gene 1 protein, Long transient receptor potential channel 2, LTrpC2, Transient receptor potential channel 7, TrpC7, Transient receptor potential melastatin 2

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Homo sapiens (taxid:9606)
	gene: TRPM2, EREG1, KNP3, LTRPC2, TRPC7 expression_system_common: Human

Authors :

Du, J., Lu, W., Huang, Y.

Keywords :

TRPM2 channel, 8-Br-cADPR, calcium, TRANSPORT PROTEIN

Exp. method :

ELECTRON MICROSCOPY ( 3.7 Å )

Citation :

Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.

Huang, Y.,Roth, B.,Lu, W. et al.
(2019) Elife 8

PDB ID: 6PUU