Het-PDB Navi2 (PDB: 6PQP)

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Ligands
Code	Name		Link
6OU	[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate		PoSSuM
9BE	N-benzylthioformamide		PoSSuM
LBN	1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine		PoSSuM
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose		PoSSuM
		: Polysaccharide

Non-standard Residues
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Download interaction data: 6PQP

Code :

6PQP PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist BITC

Release Data :

2020-01-08

Compound :

mol_id	molecule	chains	synonym
1	Transient receptor potential cation channel subfamily A member 1	A,D,B,C	Ankyrin-like with transmembrane domains protein 1,Transformation-sensitive protein p120

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Homo sapiens (taxid:9606)
	gene: TRPA1, ANKTM1 expression_system_common: Human

Authors :

Suo, Y., Wang, Z., Zubcevic, L., Hsu, A.L., He, Q., Borgnia, M.J., Ji, R.-R., Lee, S.-Y.

Keywords :

Ion channel, TRP channel, TRPA channel, TRPA1 channel, irritant sensing, BITC, membrane protein, TRANSPORT PROTEIN

Exp. method :

ELECTRON MICROSCOPY ( 3.06 Å )

Citation :

Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.

Suo, Y.,Wang, Z.,Zubcevic, L. et al.
(2020) Neuron 105 : 882

Chain :

A, D, B, C

UniProt :

O75762 (TRPA1_HUMAN)

PDB ID: 6PQP